Is the Brain the Alternative Therapeutic Target for Heart Failure?
نویسندگان
چکیده
منابع مشابه
[Mitochondrial dynamics: a potential new therapeutic target for heart failure].
Mitochondria are dynamic organelles able to vary their morphology between elongated interconnected mitochondrial networks and fragmented disconnected arrays, through events of mitochondrial fusion and fission, respectively. These events allow the transmission of signaling messengers and exchange of metabolites within the cell. They have also been implicated in a variety of biological processes ...
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برد عددی ماتریس مربعی a را با w(a) نشان داده و به این صورت تعریف می کنیم w(a)={x8ax:x ?s1} ، که در آن s1 گوی واحد است. در سال 2009، راسل کاردن مساله برد عددی معکوس را به این صورت مطرح کرده است : برای نقطه z?w(a)، بردار x?s1 را به گونه ای می یابیم که z=x*ax، در این پایان نامه ، الگوریتمی برای حل مساله برد عددی معکوس ارانه می دهیم.
15 صفحه اولPhosphodiesterase 2 as a Therapeutic Target for Heart Failure: Is Upregulation an Option?
Heart failure (HF) is a chronic progressive cardiac disease with high morbidity and mortality. A key pathophysiological feature of HF is chronic overexcitation of the sympathetic nervous system and release of catecholamines. The subsequent activation of cardiac β-adrenoceptors (β-ARs) results in molecular and structural changes that lead to cardiac hypertrophy, myocardial fibrosis, or electrome...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2016
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-16-0632